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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK1 All Species: 17.88
Human Site: Y1623 Identified Species: 30.26
UniProt: Q7Z5N4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z5N4 NP_689957.3 2213 242076 Y1623 I Y Y R E L E Y E A G S G T E
Chimpanzee Pan troglodytes XP_518946 2168 238269 Y1578 I Y Y R E L E Y E A G S G T E
Rhesus Macaque Macaca mulatta XP_001105243 2118 232418 P1545 S V L I Q W Q P P R D E S L N
Dog Lupus familis XP_547004 2144 235913 T1563 E S E A S A A T V S K T L K T
Cat Felis silvestris
Mouse Mus musculus Q3UH53 2193 240287 S1605 I Y Y R E L E S E T G M S P E
Rat Rattus norvegicus XP_001073292 2181 239558 S1593 I Y Y R E L E S E T G L S P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 E1559 N P S A L R A E I S P Q S S F
Chicken Gallus gallus Q8AV58 2169 239459 Y1575 I Y Y R E L D Y D A G S A T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686686 2126 234665 T1555 S Q L R T E L T A K S T V K T
Tiger Blowfish Takifugu rubipres Q98902 1277 141937 N706 R F R V I A I N D Q G K S D P
Fruit Fly Dros. melanogaster O97394 2224 246236 L1617 Y R I L Y Q Q L S D F P T A L
Honey Bee Apis mellifera XP_623565 2176 242722 V1574 Y R V I Y Q P V S D F P T A L
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 S1613 I H Y R E Y P S N E T W Q M E
Sea Urchin Strong. purpuratus XP_781559 2931 322437 D1944 V H K R M T P D E R V N G T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 91.5 86.7 N.A. 89.7 87.3 N.A. 79.6 78.9 N.A. 66 20.5 36.3 36.3 26.1 20.7
Protein Similarity: 100 96.1 93 91.5 N.A. 94 92 N.A. 87.8 87.8 N.A. 79.8 33.5 53.5 53.5 43.8 37.1
P-Site Identity: 100 100 0 0 N.A. 66.6 66.6 N.A. 0 80 N.A. 6.6 6.6 0 0 33.3 33.3
P-Site Similarity: 100 100 13.3 13.3 N.A. 66.6 66.6 N.A. 13.3 93.3 N.A. 13.3 20 6.6 0 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 15 15 0 8 22 0 0 8 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 15 15 8 0 0 8 0 % D
% Glu: 8 0 8 0 43 8 29 8 36 8 0 8 0 0 50 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 15 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 43 0 22 0 0 % G
% His: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 43 0 8 15 8 0 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 8 8 8 0 15 0 % K
% Leu: 0 0 15 8 8 36 8 8 0 0 0 8 8 8 15 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 8 0 8 0 % M
% Asn: 8 0 0 0 0 0 0 8 8 0 0 8 0 0 8 % N
% Pro: 0 8 0 0 0 0 22 8 8 0 8 15 0 15 8 % P
% Gln: 0 8 0 0 8 15 15 0 0 8 0 8 8 0 0 % Q
% Arg: 8 15 8 58 0 8 0 0 0 15 0 0 0 0 0 % R
% Ser: 15 8 8 0 8 0 0 22 15 15 8 22 36 8 0 % S
% Thr: 0 0 0 0 8 8 0 15 0 15 8 15 15 29 15 % T
% Val: 8 8 8 8 0 0 0 8 8 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % W
% Tyr: 15 36 43 0 15 8 0 22 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _